Bo Xia

The Xia lab seeks to address one of biology’s central questions: how does the human genome control the identity and function of thousands of cell types, and what goes wrong with the cells in conditions like aging and cancer? In our lab, we combine state-of-the-art multimodal artificial intelligence (AI) technologies and high-throughput experimental techniques to decode the regulatory logic of the genome, predict cellular responses to perturbations, and perform large-scale in silico experimentation before validating them in the lab to accelerate discoveries. We aim to understand the core regulatory program that determine cell fates, and engineer these programs to open new possibilities for regenerative medicine, aging research, and cancer therapy.